Thermo Fisher Scientific ZNF667 Polyclonal Antibody
ZNF667 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot 및 면역세포염색(ICC/IF)에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 인간 단백질에 반응하며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ZNF667. Recombinant protein control fragment (Product # RP-95766) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2663515 |
Product Specific Information
Immunogen sequence:
APWMVEPVRRR RAPDSGSKCE TKKLPPNQCN KSGQSICQKL VSAQQKAPTR KSGCNKNSVL VKPKKGHSGK
Highest antigen sequence identity to the following orthologs:
- Mouse: 66%
- Rat: 70%
Target Information
Mipu1, also known as zinc finger protein 667 (ZNF667), encodes a nuclear-localized protein containing 14 carboxy-terminal zinc finger motifs and an amino-terminal KRAB domain.
This protein is highly expressed in heart and brain and is upregulated in rat heart after transient ischemia-reperfusion.
Overexpression experiments suggest that Mipu1 suppresses transcriptional activities of AP-1 and SRE in the MAPK signaling pathway, potentially influencing cardiac and vascular disease pathogenesis.
At least four isoforms of MIPU1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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