Thermo Fisher Scientific FOG1/ZFPM1 Polyclonal Antibody
FOG1/ZFPM1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, IP 등 다양한 응용에 사용 가능. 인체 시료 반응성, 항원 친화 크로마토그래피 정제, 4°C 보관. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 175 and 225 of human Friend of GATA-1 (zinc finger protein, multitype 1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
Target Information
ZFPM1 (Friend of GATA-1) is a transcription regulator essential for erythroid and megakaryocytic cell differentiation.
It functions as a cofactor forming heterodimers with GATA family transcription factors (GATA1, GATA2, GATA3).
These heterodimers can activate or repress transcription depending on cellular and promoter context.
They are essential for activation of genes such as NFE2, ITGA2B, alpha- and beta-globin, and for repression of KLF1.
ZFPM1 may also regulate genes in gonadal tissues and play a role in cardiac development alongside ZFPM2/FOG2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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