Thermo Fisher Scientific PTH1R Polyclonal Antibody
Rabbit polyclonal antibody against human PTH1R for IHC and IHC (Paraffin) applications. Detects Parathyroid Hormone Receptor 1 with high specificity. Supplied as liquid form at 1 mg/mL concentration. Suitable for research use only.
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Applications
Immunohistochemistry (IHC)
- Tested dilution: Not specified
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested dilution: 2–4 µg/mL
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminal extracellular domain of human Parathyroid Hormone Receptor 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2173363 |
Product Specific Information
PA1-20597 detects Parathyroid Hormone Receptor 1 in human samples.
Target Information
Parathyroid hormone receptor 1 (PTH1R) is a member of the G-protein coupled receptor family. It acts as a receptor for parathyroid hormone (PTH) and parathyroid hormone-like hormone (PTHLH). The receptor activity is mediated by G proteins that activate adenylyl cyclase and the phosphatidylinositol-calcium second messenger system.
Defects in PTH1R are associated with Jansen’s metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), and enchondromatosis.
Expression has been reported in bone, breast, brain, colon, gastrointestinal tract, kidney, liver, placenta, skin, umbilical cord, and uterus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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