Thermo Fisher Scientific Human Transferrin Polyclonal Antibody, Biotin

Applications

Western Blot (WB)

• Tested Dilution: 1:10,000 - 1:100,000

ELISA

• Tested Dilution: 1:10,000 - 1:100,000

Product Specifications

Product Specific Information

Goats were immunized with purified human transferrin of serum or plasma origin.
The antibody was isolated by affinity chromatography using antigen coupled to agarose beads.
Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

Target Information

Transferrins (Tf) are approximately 80 kDa blood plasma glycoproteins synthesized by the liver.
They are iron-binding transport proteins capable of binding two Fe(3+) ions with an associated anion, typically bicarbonate.
Transferrin is responsible for iron transport from absorption and heme degradation sites to storage and utilization sites.
Under normal conditions, about one-third of total blood transferrin contains bound iron.
Measurement of transferrin levels serves as an indicator of iron metabolism and related disorders such as anemia, iron overload, and hemochromatosis.
Serum transferrin may also play a role in stimulating cell proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.