
Thermo Fisher Scientific MAPK13 Monoclonal Antibody (OTI2G5), TrueMAB
MAPK13 단백질을 인식하는 Mouse monoclonal antibody. Western blot과 Immunocytochemistry에 최적화되어 있으며, Human 시료에 반응. Lyophilized 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G5 |
| Immunogen | Full length human recombinant protein of human MAPK13 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
When using this carrier-free antibody for conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces extracellular signals, including cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by environmental stresses and proinflammatory cytokines through phosphorylation or autophosphorylation triggered by MAP3K7IP1/TAB1 interaction.
Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, implicating roles in stress-related transcription, cell cycle regulation, and genotoxic stress response.
Four alternatively spliced transcript variants of SAPK4 encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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