Thermo Fisher Scientific Collagen Type V Polyclonal Antibody
Rabbit polyclonal antibody targeting Collagen Type V from human and bovine placenta. Suitable for WB, IHC, ELISA, and IP applications. High specificity with negligible cross-reactivity to other collagen types. Supplied as liquid, 1 mg/mL, unconjugated,...
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Collagen Type V Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1:5,000–1:50,000 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Bovine, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Collagen Type V from human and bovine placenta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at 4°C prior to opening. Stable at 4°C as undiluted liquid.
- For extended storage, mix with equal volume of glycerol, aliquot, and freeze at -20°C or below.
- Avoid freeze/thaw cycles.
- Negligible cross-reactivity against other collagen types (I, II, III, IV, VI).
- Reacts with most mammalian Type V collagens.
- Minimal non-specific binding to serum or extracellular matrix proteins.
Target Information
Type I collagen is a fibrillar collagen found in most connective tissues and is a key component of cartilage. Mutations in the Type I collagen gene are linked to osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis.
Chromosomal translocations between chromosomes 17 and 22 involving this gene and PDGF beta gene are associated with dermatofibrosarcoma protuberans due to unregulated growth factor expression.
Two transcripts have been identified from alternate polyadenylation signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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