Thermo Fisher Scientific Collagen Type V Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Store vial at 4°C prior to opening. Stable at 4°C as undiluted liquid.
• For extended storage, mix with equal volume of glycerol, aliquot, and freeze at -20°C or below.
• Avoid freeze/thaw cycles.
• Negligible cross-reactivity against other collagen types (I, II, III, IV, VI).
• Reacts with most mammalian Type V collagens.
• Minimal non-specific binding to serum or extracellular matrix proteins.

Target Information

Type I collagen is a fibrillar collagen found in most connective tissues and is a key component of cartilage. Mutations in the Type I collagen gene are linked to osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis.
Chromosomal translocations between chromosomes 17 and 22 involving this gene and PDGF beta gene are associated with dermatofibrosarcoma protuberans due to unregulated growth factor expression.
Two transcripts have been identified from alternate polyadenylation signals.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.