Thermo Fisher Scientific NKG2A Polyclonal Antibody
Thermo Fisher Scientific의 NKG2A Polyclonal Antibody는 인간 KLRC1 단백질을 인식하는 토끼 IgG 항체로, WB, IHC, ICC/IF 등 다양한 실험에 적용 가능합니다. 고순도 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보관됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KLRC1 (Accession P26715), corresponding to amino acid residues M1–Y40 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900118 |
Product Specific Information
Antibody detects endogenous levels of total KLRC1.
Target Information
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They also regulate specific humoral and cell-mediated immunity.
The protein encoded by this gene belongs to the killer cell lectin-like receptor family (NKG2 family), a group of transmembrane proteins preferentially expressed in NK cells. These proteins have a type II membrane orientation and contain a C-type lectin domain.
This protein forms a complex with KLRD1/CD94 and is involved in recognition of MHC class I HLA-E molecules in NK cells. The NKG2 gene family forms a lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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