Thermo Fisher Scientific SARS-CoV-2 membrane glycoprotein Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1:10,000

-

Immunoprecipitation (IP)

1:50-1:250

-

Product Specifications

Species Reactivity

Virus

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide taken from unique amino acid sequence on membrane glycoprotein [Severe acute respiratory syndrome coronavirus 2].

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Target Information

The M glycoprotein is the most abundant envelope protein of SARS-CoV-2. In silico analyses of the M protein of SARS-CoV-2 using Protter demonstrated that it has a triple-helix bundle, and forms a single 3-transmembrane domain. It has been reported that SARS-CoV-2 membrane glycoprotein M may function as a negative regulator of the innate immune response. It is suggested that the M protein interacted with the central adaptor protein MAVS in the innate immune response pathways.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.