Thermo Fisher Scientific CXCL11 Polyclonal Antibody
CXCL11 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 사용 가능. 인간 시료에 반응하며, 고순도의 액상 형태로 제공. PBS buffer(50% glycerol) 보존, -20°C 보관. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CXCL11 (Accession O14625), corresponding to amino acid residues M51–F94. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853475 |
Product Specific Information
Antibody detects endogenous levels of total CXCL11.
Target Information
Interferon-inducible T-cell alpha chemoattractant (I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas, liver, thymus, spleen, lung, small intestine, placenta, and prostate.
Its molecular weight is 8–11 kDa. I-TAC is also known as CXCL-11 and IP-9.
This cytokine regulates calcium release and induces chemotactic responses in activated T-cells, acting as the dominant ligand for CXC receptor-3.
The gene encoding this protein contains 4 exons and at least three polyadenylation signals, which may reflect cell-specific regulation of expression.
IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia, and multiple sclerosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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