Thermo Fisher Scientific SLC6A11 Polyclonal Antibody
SLC6A11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, 인간·마우스·랫트 시료에서 반응. 액상 형태로, PBS와 글리세롤 버퍼에 저장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SLC6A11 (Accession P48066), corresponding to amino acid residues L406–T456 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853478 |
Product Specific Information
Antibody detects endogenous levels of total SLC6A11.
Target Information
Slc6a11 encodes GABA transporters that are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6). These transporters mediate rapid removal of GABA to maintain low extracellular levels.
Four 12-transmembrane domain transporters have been identified and localized to neurons and glia.
The protein encoded by the Slc6a11 gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, terminating GABA neurotransmission.
Defects in the Slc6a11 gene may lead to epilepsy, behavioral, or intellectual disorders. Two transcript variants encoding different isoforms have been found.
Diseases associated with SLC6A11 include Tricuspid Valve Stenosis and Pulmonary Valve Insufficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-104150_SLC6A11_P48066-1_Rabbit_PDP.jpeg)
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