Thermo Fisher Scientific FLT3 Monoclonal Antibody (OTI7D6), TrueMAB
Human 및 Mouse 반응성을 가지는 FLT3 단클론 항체로, Western blot에 적합합니다. 항체는 Lyophilized 형태이며, 재구성 후 1 mg/mL 농도 유지가 가능합니다. PBS 기반 버퍼에 8% trehalose를 포함하며, 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7D6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 169–444 of human FLT3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
FLT3 is a tyrosine protein kinase belonging to the growth factor receptor tyrosine kinase family. It is activated by binding of the FLT3 ligand, leading to homodimer formation and autophosphorylation. The activated receptor phosphorylates and activates downstream molecules involved in apoptosis, proliferation, and differentiation of hematopoietic cells. Constitutive activation due to mutations is associated with acute myeloid leukemia and acute lymphoblastic leukemia.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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