Thermo Fisher Scientific CD170 (Siglec F) Monoclonal Antibody (3F5A3)
CD170 (Siglec F) 단클론 항체로 인간 시료에 반응하며 Western blot, Flow cytometry, ELISA에 적합. Mouse IgG2a 형식의 비표지 항체로, 고순도 Protein G 정제. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3F5A3 |
| Immunogen | Purified recombinant fragment of human CD170 (AA: extra 17–230) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091013 |
Target Information
SIGLEC5 is a putative adhesion molecule that mediates sialic acid-dependent binding to cells. It binds equally to α2,3-linked and α2,6-linked sialic acid. The recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells and is found at high levels in peripheral blood leukocytes, spleen, and bone marrow, with lower levels in lymph node, lung, appendix, placenta, pancreas, and thymus. It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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