Thermo Fisher Scientific COPS6 Monoclonal Antibody (OTI2F5), TrueMAB
COPS6 단백질을 인식하는 Mouse monoclonal 항체로 Western blot과 IHC(P) 실험에 적합합니다. Human 시료에 반응하며, 고순도의 Affinity chromatography 정제 제품입니다. PBS/BSA/glycerol buffer에 보관되며 -20°C에서 안정적입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 58–327 of human COPS6 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that regulates multiple signaling pathways. Its structure and function are similar to the 19S regulatory particle of the 26S proteasome. COP9 signalosome interacts with SCF-type E3 ubiquitin ligases and acts as a positive regulator. This protein belongs to the translation initiation factor 3 superfamily, is involved in cell cycle regulation, and may serve as a cofactor for the HIV-1 accessory gene product Vpr.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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