Thermo Fisher Scientific FAM3B Polyclonal Antibody
Rabbit polyclonal antibody against human FAM3B protein. Validated for ICC/IF applications. Suitable for detecting FAM3B expression in human tissues. Antigen affinity purified and supplied in PBS with glycerol. For research use only.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human FAM3B. Recombinant protein control fragment (Product #RP-105814) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2663028 |
Product Specific Information
- Immunogen sequence: AELIPDAPLSS AAYSIRSIGE RPVLKAPV
- Highest antigen sequence identity: Mouse 83%, Rat 83%
Target Information
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11, or PANDER, is a 235 amino acid secreted protein localized to discrete vesicular and perinuclear structures. It is highly expressed in the pancreas and at lower levels in kidney, colon, testis, prostate, and small intestine. FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit insulin secretion from beta-cells, suggesting a role in pancreatic activity. Human FAM3B shares 78% sequence identity with mouse FAM3B, indicating a conserved function. Three isoforms (A, B, and C) exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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