Thermo Fisher Scientific FIBB Polyclonal Antibody
Human FGB 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 0.5 mg/mL 농도 제공. 연구용으로만 사용되며, 혈액 응고 관련 단백질 연구에 적합.
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Thermo Fisher Scientific FIBB Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:5,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FGB. Recombinant protein control fragment (Product #RP-100424) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789149 |
Product Specific Information
Immunogen sequence:
ERKAPDAGGC LHADPDLGVL CPTGCQLQEA LLQQERPIRN SVDELNNNVE AVSQTSSSSF QYMYLLKDLW QKRQKQVKDN ENVVNEYSSE LEKHQLYIDE TVNSNIPTNL RVLRSILENL RSKIQKLE
Target Information
FIBB is the beta component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the major component of blood clots. Fibrinogen and fibrin cleavage products regulate cell adhesion and spreading, act as vasoconstrictors and chemotactic agents, and serve as mitogens for various cell types. Mutations in the FGB gene are associated with disorders such as afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia, and thrombotic tendency.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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