Thermo Fisher Scientific CACNG3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide (C)RSHSELLKKSTFAR, corresponding to amino acid residues 210-223 of rat CaV gamma3 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CACNG3,uniProtId:Q8VHX0-1,ncbiNodeId:10114,antigenRange:210-223,antigenLength:315,antigenImageFileName:PA5-77349_CACNG3_Q8VHX0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-77349_CACNG3_Q8VHX0-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.8 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2735555

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.

Target Information

Calcium Channel gamma-3 is a member of voltage dependent calcium channels (VDCCs) which allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal, and important in the genesis of synaptic transmission in discrete hippocampal fields. Calcium Channel gamma-3 is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. Further, Calcium Channel gamma-3 is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. Calcium Channel gamma-3 gene dysfunction is a susceptibility locus for childhood absence epilepsy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.