Thermo Fisher Scientific CD53 Polyclonal Antibody
CD53 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 반응성. WB 및 ICC/IF에 적합하며, 고순도 친화 크로마토그래피 정제. 액상 형태, -20°C 보관, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CD53 (Accession P19397), corresponding to amino acid residues N46–E96 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899622 |
Product Specific Information
Antibody detects endogenous levels of total CD53.
Target Information
CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage.
It forms complexes with leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4, or tetraspanins CD37, CD81, and CD82, modulating various signaling processes.
CD53 contributes to tumor cell radioresistance and exerts anti-apoptotic effects upon activation.
In thymus, CD53 expression increases during T cell positive selection and is strongly induced in macrophages exposed to bacterial lipopolysaccharides, while neutrophil stimulation down-regulates CD53 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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