Thermo Fisher Scientific HSD3B7 Polyclonal Antibody
Human HSD3B7 단백질을 인식하는 Rabbit Polyclonal Antibody로 IHC(P) 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS와 40% 글리세롤 버퍼에 보존. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HSD3B7. Recombinant protein control fragment (Product #RP-101137). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642569 |
Product Specific Information
- Immunogen sequence:
VVRMLLQREP RLGELRVFDQ HLGPWLEELK TGPVRVTAIQ GDVTQAHEVA AAVAGAHVVI HTAGLVDVFG RASPKTIHEV NVQG - Highest antigen sequence identity:
- Mouse: 85%
- Rat: 85%
Target Information
This gene encodes an enzyme involved in the initial stages of bile acid synthesis from cholesterol and belongs to the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum enzyme active against 7-alpha-hydroxylated sterol substrates. Mutations in this gene are associated with congenital bile acid synthesis defects leading to neonatal cholestasis, a progressive liver disease. Multiple transcript variants encoding different isoforms have been identified.
[provided by RefSeq, Dec 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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