
Thermo Fisher Scientific Cas9 Recombinant Superclonal Antibody (12HCLC)
Streptococcus pyogenes Cas9 단백질을 인식하는 Recombinant Superclonal™ 항체. 폴리클로날의 감도와 모노클로날의 특이성을 결합한 재조합 항체로, 일관된 로트 간 재현성 제공. Western blot 등 세균 Cas9 검출에 적합.
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Applications
- Western Blot (WB): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bacteria |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 12HCLC |
| Immunogen | Full length protein corresponding to Streptococcus pyogenes Cas9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2605799 |
Product Specific Information
This antibody was tested in Streptococcus pyogenes bacteria.
Recombinant rabbit Superclonal™ antibodies are composed of multiple recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies and the consistency of recombinant production.
These antibodies recognize multiple epitopes on the target, providing high detection sensitivity for low-abundance targets, while maintaining lot-to-lot reproducibility.
Formerly known as “Recombinant polyclonal antibody”, this product has been rebranded as “Recombinant Superclonal™ antibody” without changes in physical or performance characteristics.
Target Information
Cas9 is an RNA-guided DNA endonuclease enzyme associated with the CRISPR adaptive immunity system in bacteria and is widely used in genetic engineering.
Cas9 enables targeted genome editing, including indel mutations, sequence insertions, deletions, and rearrangements.
Variants such as Streptococcus pyogenes Cas9 (SpCas9) and Staphylococcus aureus Cas9 (SaCas9) differ in size and PAM recognition sequences.
SaCas9 recognizes NNGRRT PAM, exhibits high efficiency and specificity, and is suitable for compact delivery systems, such as AAV vectors.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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