Thermo Fisher Scientific NUP210L Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human NUP210L(Accession Q5VU65), corresponding to amino acid residues N1016-D1066. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NUP210L,uniProtId:Q5VU65-1,ncbiNodeId:9606,antigenRange:1016-1066,antigenLength:1888,antigenImageFileName:PA5-115678_NUP210L_Q5VU65-1_Rabbit.svg,antigenImageFileNamePDP:PA5-115678_NUP210L_Q5VU65-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2900313

Product Specific Information

Antibody detects endogenous levels of total NUP210L.

Target Information

Nup210L (nuclear pore membrane glycoprotein 210-like) is a 1,888 amino acid single-pass membrane protein that belongs to the NUP210 family. The gene that encodes Nup210L consists of approximately 162,432 bases and maps to human chromosome 1q21.3. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.