Thermo Fisher Scientific Phospho-DAB1 (Tyr198) Polyclonal Antibody
Phospho-DAB1 (Tyr198) 항체로 인산화된 Dab1 단백질을 특이적으로 검출. Western blot 및 IHC(파라핀 절편) 실험에 적합. 사람, 생쥐, 랫드 반응성. Rabbit Polyclonal 형식으로 1 mg/mL 농도 제공. -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DAB1 (Accession O75553), corresponding to amino acid residues around phosphorylated Tyr198 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816856 |
Product Specific Information
Antibody detects endogenous levels of Dab1 only when phosphorylated at Tyr198.
Target Information
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function.
In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer.
This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain.
Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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