Thermo Fisher Scientific ADD1 Polyclonal Antibody, MaxPab

Thermo Fisher Scientific ADD1 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB)
  Tested Dilution: 1–5 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MNGDSRAAVV TSPPPTTAPH KERYFDRVDE NNPEYLRERN MAPDLRQDFN MMEQKKRVSM ILQSPAFCEE LESMIQEQFK KGKNPTGLLA LQQIADFMTT NVPNVYPAAP QGGMAALNMS LGMVTPVNDL RGSDSIAYDK GEKLLRCKLA AFYRLADLFG WSQLIYNHIT TRVNSEQEHF LIVPFGLLYS EVTASSLVKI NLQGDIVDRG STNLGVNQAG FTLHSAIYAA RPDVKCVVHI HTPAGAAVSA MKCGLLPISP EALSLGEVAY HDYHGILVDE EEKVLIQKNL GPKSKVLILR NHGLVSVGES VEEAFYYIHN LVVACEIQVR TLASAGGPDN LVLLNPEKYK AKSRSPGSPV GEGTGSPPKW QIGEQEFEAL MRMLDNLGYR TGYPYRYPAL REKSKKYSDV EVPASVTGYS FASDGDSGTC SPLRHSFQKQ QREKTRWLNS GRGDEASEEG QNGSSPKSKT KWTKEDGHRT STSAVPNLFV PLNTNPKEVQ EMRNKIREQN LQDIKTAGPQ SQVLCGVVMD RSLVQDAPLS DCTETIEGLE LTEQTFSPAK SLSFRKGELV TASKAIIEKE YQPHVIVSTT GPNPFTTLTD RELEEYRREV ERKQKGSEEN LDEAREQKEK SPPDQPAVPH PPPSTPIKLE EGDGCAREYL LP

Target Information

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein composed of related subunits produced from distinct genes but sharing similar structure.
Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region.
Alpha- and gamma-adducins are ubiquitously expressed, while beta-adducin is highly expressed in brain and hematopoietic tissues.
Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.
Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.