Thermo Fisher Scientific ADCY5 Monoclonal Antibody (3E6)
ADCY5 단백질을 인식하는 Mouse IgG2b 단일클론 항체로 Western blot과 ELISA에 적합. 인간 시료 반응성이 있으며, PBS 용액 형태로 제공. 연구용으로 G단백질 연관 신호전달 관련 연구에 활용 가능.
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Thermo Fisher Scientific ADCY5 Monoclonal Antibody (3E6)
Applications and Tested Dilution
- Western Blot (WB): 1–5 µg/mL
- ELISA: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E6 |
| Immunogen | ADCY5 (NP_899200, 1152–1261 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:ADFAMKLMDQ MKYINEHSFN NFQMKIGLNI GPVVAGVIGA RKPQYDIWGN TVNVASRMDS TGVPDRIQVT TDMYQVLAAN TYQLECRGVV KVKGKGEMMT YFLNGGPPLS
Target Information
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium, and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
[Provided by RefSeq, Dec 2010]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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