Thermo Fisher Scientific ADCY5 Monoclonal Antibody (3E6)

Thermo Fisher Scientific ADCY5 Monoclonal Antibody (3E6)

Applications and Tested Dilution

• Western Blot (WB): 1–5 µg/mL
• ELISA: 1 ng/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
ADFAMKLMDQ MKYINEHSFN NFQMKIGLNI GPVVAGVIGA RKPQYDIWGN TVNVASRMDS TGVPDRIQVT TDMYQVLAAN TYQLECRGVV KVKGKGEMMT YFLNGGPPLS

Target Information

This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium, and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
[Provided by RefSeq, Dec 2010]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.