Thermo Fisher Scientific MANF Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat

Target Information

The protein encoded by this gene is localized in the endoplasmic reticulum and Golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region, but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. Polymorphisms in the arginine-rich region, including a mutation changing codon 50 from ATG to AGG, have been reported in various solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.