Thermo Fisher Scientific ERCC1 Polyclonal Antibody
ERCC1 단백질을 인식하는 염소 유래 폴리클로날 항체로, 사람 시료에 반응합니다. IHC 및 ICC/IF 등 다양한 응용에 적합하며, 고순도 암모늄 황산 침전으로 정제되었습니다. DNA 복구 관련 연구에 활용 가능하며 연구용으로만 사용됩니다.
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Thermo Fisher Scientific ERCC1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-QVDVKDPQQALKE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932964 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:4,000.
Target Information
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5′-incision during DNA repair. It works with SLX4 in repairing interstrand cross-links (ICL) and participates in the processing of anaphase bridge-generating DNA structures that can lead to cytokinesis failure. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. (Uniprot)
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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