Thermo Fisher Scientific COL5A3 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 1:1,000

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total COL5A3.

Target Information

Type I collagen is a fibrillar collagen found in most connective tissues and is the only collagen component in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from alternate polyadenylation signals, have been identified for this gene.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.