Thermo Fisher Scientific Trop2 (EGP-1) Monoclonal Antibody (MR54), PE, eBioscience
인간 Trop-2 단백질을 인식하는 MR54 단클론 항체로, PE 형광표지되어 유세포분석(Flow Cytometry)에 적합합니다. Affinity chromatography로 정제되었으며, 4°C 암소 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- Application: Flow Cytometry (Flow)
- Tested Dilution: 5 µL (0.125 µg)/test
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Recommended Isotype Control | Mouse IgG2a kappa Isotype Control (eBM2a), PE, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MR54 |
| Conjugate | PE |
| Excitation/Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2572648 |
Additional Formats
Product Specific Information
Description:
This MR54 monoclonal antibody reacts with human Trop-2 (Tumor-Associated Calcium Signal Transducer 2, TACSTD2, EGP-1). Trop-2 is a type I transmembrane glycoprotein expressed on trophoblasts, epithelial cells, and most human carcinoma cells. It plays a role in calcium-mediated signaling and has been reported as an oncogene correlated with tumorigenesis, metastasis, and anchorage-independent growth.
Applications Reported:
This MR54 antibody is reported for use in flow cytometric analysis.
Applications Tested:
Pre-titrated and tested by flow cytometric analysis of MCF7 cells. Recommended usage: 5 µL (0.125 µg) per test (100 µL final volume). Applicable cell number: 10⁵–10⁸ cells/test.
Excitation/Emission:
- Excitation: 488–561 nm
- Emission: 578 nm
- Compatible Lasers: Blue, Green, Yellow-Green
Filtration:
0.2 µm post-manufacturing filtered.
Target Information
TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. It is a type I membrane protein that transduces intracellular calcium signals and functions as a cell surface receptor. Mutations in its gene cause gelatinous drop-like corneal dystrophy, an autosomal recessive disorder leading to corneal amyloidosis and blindness.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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