Thermo Fisher Scientific hnRNP L Polyclonal Antibody
Rabbit polyclonal antibody against hnRNP L for WB, IHC, and ICC applications. Recognizes human hnRNP L and predicted to react with mouse. Supplied as liquid, unconjugated form at 0.6 mg/mL. Suitable for mRNA processing and hnRNP complex studies.
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- PA519599
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 250–350 of Human hnRNP L |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11004516 |
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Target Information
Heterogeneous nuclear RNAs (hnRNAs), including mRNA precursors and mature mRNAs, associate with specific proteins to form heterogeneous ribonucleoprotein (hnRNP) complexes. hnRNP L is one of the proteins stably associated with these complexes and plays a major role in mRNA formation, packaging, processing, and function. It is present in the nucleoplasm as part of the hnRNP complex but can also be found outside the nucleoplasm. hnRNP proteins shuttle between the nucleus and cytoplasm, suggesting potential cytoplasmic functions. Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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