Thermo Fisher Scientific CD123 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1297)
CD123(IL-3Ra)을 인식하는 알파카 유래 재조합 단클론 항체로, Flow Cytometry, ELISA, SPR 등 다양한 분석에 사용 가능. CHO 세포에서 발현되었으며, 금속 킬레이트 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
- 카탈로그번호
- MA554429
- 판매단위
- pk
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Applications and Tested Dilution
Flow Cytometry (Flow)
- Assay-dependent
ELISA
- Assay-dependent
Surface Plasmon Resonance (SPR)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1297 |
| Immunogen | Recombinant Human CD123/IL3RA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and forms a heterodimer with the common beta (βc or CDw131) subunit.
IL-3Ra mediates the signal transmission of Interleukin-3. Heterodimerization of IL-3Ra and IL-3Rb chains is induced by Interleukin-3 and is required for receptor activation but not for high-affinity binding.
IL-3Ra is reported to be overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells, making it a potential target for novel therapeutic agents.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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