
Thermo Fisher Scientific P2Y12 Receptor (extracellular) Polyclonal Antibody, FITC
FITC 결합된 P2Y12 수용체 폴리클로날 항체로 인간 및 생쥐 시료에 반응. Flow Cytometry에 적합하며, 항원 친화 크로마토그래피로 정제됨. 혈소판 응집 관련 연구 및 GPCR 기능 분석에 유용.
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Applications
- Flow Cytometry (Flow): 5 µg per 0.5×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CTAENTLFYVKES (amino acids 270–282 of human P2RY12, 3rd extracellular loop) |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 50 µL of double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and keep at -20°C.
Avoid multiple freeze-thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
P2Y12 is a G-protein coupled receptor (GPCR) involved in platelet aggregation and is a potential therapeutic target for thromboembolic and clotting disorders.
It has multiple receptor subtypes with overlapping pharmacological selectivity for adenosine and uridine nucleotides.
Two transcript variants encoding the same isoform have been identified.
Expression reported in platelets, spinal cord, and various brain regions.
ESTs detected in B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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