
Thermo Fisher Scientific P2X3 Receptor Polyclonal Antibody, Atto 594
Atto 594로 표지된 P2X3 수용체 폴리클로날 항체로, 면역조직화학(IHC)에 적합. 사람, 생쥐, 랫드에 반응하며 항원 친화 크로마토그래피로 정제됨. ATP 수용체 연구 및 통증 신호전달 연구에 활용 가능.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)VEKQSTDSGAYSIGH, corresponding to amino acid residues 383–397 of rat P2X3 receptor (Intracellular, C-terminus) |
| Conjugate | Atto™ 594 |
| Excitation / Emission Max | 602 / 622 nm |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 50 µL double distilled water (DDW), depending on the sample size.
- The antibody ships as a lyophilized powder at room temperature.
- Upon arrival, store at -20°C.
- The reconstituted solution can be stored at 4°C for up to 1 week.
- For longer storage, aliquot and keep at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
The P2X3 receptor belongs to the purinoceptor family for ATP and functions as a ligand-gated ion channel. It may transduce ATP-evoked nociceptor activation. Studies in mice indicate its importance in peripheral pain responses and urinary bladder volume reflex control. Development of selective antagonists for this receptor may have therapeutic potential for pain relief and urinary disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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