Thermo Fisher Scientific PTX3 Polyclonal Antibody
PTX3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 반응성을 보임. Western blot과 ELISA에 적합하며, 고순도 친화 크로마토그래피로 정제됨. 액상 형태로 -20°C 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 18–240 of human PTX3 (NP_0028432) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.87 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805076 |
Product Specific Information
Immunogen sequence:
ENSDDYDLMY VNLDNEIDNG LHPTEDPTPC ACGQEHSEWD KLFIMLENSQ MRERMLLQAT DDVLRGELQR LREELGRLAE SLARPCAPGA PAEARLTSAL DELLQATRDA GRRLARMEGA EAQRPEEAGR ALAAVLEELR QTRADLHAVQ GWAARSWLPA GCETAILFPM RSKKIFGSVH PVRPMRLESF SACIWVKATD VLNKTILFSY GTKRNPYEIQ LYL
Positive Samples: Mouse liver
Target Information
Pentraxins are a protein superfamily characterized by a cyclic multimeric structure. PTX3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that plays a non-redundant role in resistance to selected microbial agents. PTX3 belongs to the family of long pentraxins, which have C-terminal pentraxin domains and novel amino-terminal domains.
PTX3 binds pathogens such as Aspergillus fumigatus, Pseudomonas aeruginosa, and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion of PTX3 in adipose cells can be induced by TNF. PTX3 is involved in amplification of inflammatory reactions and regulation of innate immunity. The human PTX3 gene maps to chromosome 3q25.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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