Thermo Fisher Scientific WWOX Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal WWOX 항체. Western blot과 ELISA에 사용 가능하며, recombinant fusion protein(aa 1–120)을 면역원으로 함. 액상 형태로 제공되며, -20°C 보관 및 동결/해동 회피 필요. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–120 of human WWOX (NP_0574571) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.13 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805073 |
Product Specific Information
- Immunogen sequence: MAALRYAGLD DTDSEDELPP GWEERTTKDG WVYYANHTEE KTQWEHPKTG KRKRVAGDLP YGWEQETDEN GQVFFVDHIN KRTTYLDPRL AFTVDDNPTK PTTRQRYDGS TTAMEILQGR
- Positive Samples: SKOV3, LO2, HT-29, A-549, Jurkat, Mouse brain, Rat brain
- Cellular Location: Cytoplasm, Golgi apparatus, Mitochondrion, Nucleus
Target Information
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing.
This gene encodes a protein containing 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression is detected in hormonally regulated tissues such as testis, ovary, and prostate.
The encoded protein shows >90% identity to the mouse homolog, which mediates TNF-α-induced apoptosis, suggesting a similar role in humans. Evidence indicates tumor suppressor activity, and alternative splicing produces multiple isoforms.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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