Thermo Fisher Scientific CD4 Polyclonal Antibody
Rabbit polyclonal antibody against human CD4, suitable for Western blot applications. Recognizes residues 325–375 of CD4. Unconjugated and purified by Protein G. Stored in PBS with gelatin and sodium azide, ideal for research use only.
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Applications
- Western Blot (WB): Tested dilution 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 325–375 of human CD4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.2% gelatin |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2073059 |
Product Specific Information
Suggested positive control: human thymus protein.
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in T helper cells but can also be found in monocytes, macrophages, and dendritic cells. Tissue-level expression includes thymus, lymph nodes, tonsils, spleen, and specific regions of the brain and gut. CD4 assists in early T-cell activation through association with the T-cell receptor complex and Lck kinase and may mediate neuronal damage in infectious or immune-related CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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