Thermo Fisher Scientific MTHFD1 Polyclonal Antibody
인간 및 생쥐 MTHFD1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 액상 형태로 1 mg/mL 농도, PBS와 50% glycerol 저장 버퍼를 포함합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MTHFD1 (Accession P11586), corresponding to amino acid residues K299–G349 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900233 |
Product Specific Information
Antibody detects endogenous levels of total MTHFD1.
Target Information
This gene encodes a protein that possesses three distinct enzymatic activities:
- 5,10-methylenetetrahydrofolate dehydrogenase
- 5,10-methenyltetrahydrofolate cyclohydrolase
- 10-formyltetrahydrofolate synthetase
Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses.
The trifunctional enzymatic activities are conferred by two major domains:
- An aminoterminal portion containing the dehydrogenase and cyclohydrolase activities
- A larger synthetase domain
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-115598_MTHFD1_P11586-1_Rabbit.svg)
(이미지: PA5-115598_MTHFD1_P11586-1_Rabbit_PDP.jpeg)
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