Thermo Fisher Scientific TIA-1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human TIA-1 protein. Validated for WB and IP applications. Supplied as liquid, 0.5 mg/mL, purified by affinity chromatography. Recommended storage at -20°C with sucrose and sodium azide preservative.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunoprecipitation (IP) | 1:200 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human TIA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2884229 |
Product Specific Information
Immunogen sequence:
QAWNQQGFNQ TQSSAPWMGP NYGVQPPQGQ NGSMLPNQPS GYRVAGYETQ
- For short-term use, store at 2–8°C for up to 1 week.
- For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology:
Cow: 82%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 93%
Target Information
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through signals from WNT3A (to stabilize beta-catenin) and Noggin, a bone morphogenetic protein inhibitor. Mutations in Noggin are associated with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1), characterized by multiple joint fusions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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