Thermo Fisher Scientific ISL1 Monoclonal Antibody (OTI6E8), TrueMAB
ISL1 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, Western blot에 최적화됨. 인간 단백질 134–349 아미노산 구간을 면역원으로 사용. Carrier-free 형태로 재결합 및 conjugation 실험에 적합. -20°C 보관, 연구용 전용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 134–349 of human ISL1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The ISL1 gene encodes a member of the LIM/homeodomain transcription factor family.
The protein binds to enhancer regions of genes such as the insulin gene and plays a key role in pancreatic cell lineage development and motor neuron generation.
Mutations in ISL1 have been linked to maturity-onset diabetes of the young (MODY).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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