Thermo Fisher Scientific ISL1 Monoclonal Antibody (OTI2D8), TrueMAB
ISL1 단백질을 인식하는 마우스 단일클론 항체로, Western blot에 적합합니다. 사람 단백질에 반응하며, 무보존제 PBS 완충액에 동결건조 형태로 제공됩니다. 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 연구용으로만 사용하십시오.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 134–349 of human ISL1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The ISL1 gene encodes a member of the LIM/homeodomain family of transcription factors. This protein binds to enhancer regions of the insulin gene and plays an important role in regulating insulin gene expression. It is central to pancreatic cell lineage development and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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