Thermo Fisher Scientific Rosmantuzumab Humanized Recombinant Human Monoclonal Antibody
RSPO3를 표적으로 하는 인간화 재조합 단일클론 항체로, Wnt/β-catenin 신호 조절 연구에 적합. ELISA 등 다양한 면역분석에 사용 가능. 낮은 엔도톡신 수준과 높은 순도로 연구 신뢰성 보장. 장기 보관 시 -20°C 이하에서 안정적.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human RSPO3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.72 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.5 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911271 |
Product Specific Information
- Endotoxin level < 0.01 EU/µg by LAL method
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Rosmantuzumab is a biosimilar that targets RSPO3, a member of the R-spondin family.
RSPO3 regulates Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth, and disease pathogenesis.
It plays a role in balancing angioblast and blood cell specification during embryonic vasculogenesis and angiogenesis, and may be associated with tumor development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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