Thermo Fisher Scientific GTF2B Monoclonal Antibody (OTI2A1), TrueMAB
인간 GTF2B 단백질(aa 43-316)에 특이적인 Mouse monoclonal antibody. Western blot에 적합하며, 1:2,000 희석 권장. PBS, 1% BSA, 50% glycerol 용액에 보관. -20°C에서 보관하며 동결/해동 반복은 피해야 함.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 43-316 of human GTF2B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Ubiquitin is a 76 amino acid highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. This process regulates the concentration of key regulatory proteins by limiting their lifespans. Polyubiquitination is a common feature of this modification. The modification involves activation of ubiquitin by E1, transfer to E2, and covalent linkage to target proteins directly or via E3 ligase. Deubiquitination enzymes can reverse this process. Ubiquitin-mediated tagging is involved in diverse cellular processes including:
- Cell cycle and growth regulation
- Embryogenesis and apoptosis
- Signal transduction and DNA repair
- Transcription regulation and DNA replication
- Stress response, immune response, and nervous system functions
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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