Thermo Fisher Scientific ABCG5 Polyclonal Antibody
ABCG5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A로 정제된 1 mg/mL 액상 형태로, -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human ABCG5 (amino acids 251–350) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the ABCG5 gene belongs to the ATP-binding cassette (ABC) transporter superfamily, which transports various molecules across cellular membranes.
ABCG5 is part of the White subfamily and functions as a half-transporter that limits intestinal absorption and promotes biliary excretion of sterols.
It is expressed in the liver, colon, and intestine. The gene is located on chromosome 2, arranged head-to-head with ABCG8.
Mutations in ABCG5 can lead to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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