Thermo Fisher Scientific COPB2 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human COPB2 protein. Validated for ICC/IF applications. Supplied as a liquid, unconjugated form with 0.1 mg/mL concentration. Purified by antigen affinity chromatography and stored in PBS with 40% glycerol. For re...
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Applications
- Immunocytochemistry (ICC/IF)
Tested dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human COPB2. Recombinant protein control fragment (Product #RP-106826) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662814 |
Product Specific Information
Immunogen sequence:
GNANMVNKLAE GAERDGKNNV AFMSYFLQGK VDACLELLIR TGRLPEAAFL ARTYLPSQVS RVVKLWRENL SKVNQKAAE
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 26%
Target Information
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non–clathrin-coated vesicles, mediating biosynthetic protein transport from the ER via the Golgi to the trans-Golgi network. The coatomer complex is required for budding from Golgi membranes and is essential for retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), small GTP-binding proteins. The complex also influences Golgi structural integrity and the processing, activity, and endocytic recycling of LDL receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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