Thermo Fisher Scientific CXXC5 Polyclonal Antibody
CXXC5 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합하며, 높은 특이성과 재현성을 제공. 항원 친화 크로마토그래피로 정제되어 신뢰성 높은 연구용 데이터 확보에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CXXC5. Recombinant protein control fragment (Product #RP-105094) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663824 |
Product Specific Information
Immunogen sequence:
ASLLANGHDLA AAMAVDKSNP TSKHKSGAVA SLLSKAERAT ELAAEGQLTL QQFAQSTEML KRVVQEHLPL
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
CXXC5 is a zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax). Like CXXC4, it is thought to modulate the Wnt signaling pathway during development.
CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitating the response of the stem cells to Wnt3a.
Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together they are involved in the WNT/β-catenin pathway and play a role in embryonic kidney development.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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