Thermo Fisher Scientific GBA2 Polyclonal Antibody
Rabbit polyclonal antibody against human GBA2 protein. Suitable for IHC(P) and ICC/IF applications. Affinity purified and supplied as liquid form with PBS/glycerol buffer. For research use only, not for diagnostic procedures.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Concentration: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GBA2. Recombinant protein control fragment (Product #RP-92883). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641889 |
Product Specific Information
Immunogen sequence:
HDTADWKDLN LKFVLQVYRD YYLTGDQNFL KDMWPVCLAV MESEMKFDKD HDGLIENGGY ADQTYDGWVT TGPSAYCGGL WLAAVAVMVQ MAALCGAQDI QDKFSSILSR GQEAYERLLW NGRYYNYDSS SRPQSRSVMS DQCA
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 95%
Target Information
Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, although the relevance of such activity is unclear in vivo. Plays a role in central nervous system development and is required for proper formation of motor neuron axons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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