Thermo Fisher Scientific GBA2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GBA2. Recombinant protein control fragment (Product #RP-92883). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GBA2,uniProtId:Q9HCG7-1,ncbiNodeId:9606,antigenRange:612-755,antigenLength:927,antigenImageFileName:PA5-54955_GBA2_Q9HCG7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54955_GBA2_Q9HCG7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641889

Product Specific Information

Immunogen sequence: HDTADWKDLN LKFVLQVYRD YYLTGDQNFL KDMWPVCLAV MESEMKFDKD HDGLIENGGY ADQTYDGWVT TGPSAYCGGL WLAAVAVMVQ MAALCGAQDI QDKFSSILSR GQEAYERLLW NGRYYNYDSS SRPQSRSVMS DQCA

Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 95%.

Target Information

Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.