Thermo Fisher Scientific Kappa Light Chain (B-Cell Marker) Monoclonal Antibody (KLC264), CF 488
인간 B세포 마커인 Kappa Light Chain을 인식하는 단클론 항체. ICC/IF 및 유세포분석에 적합하며 CF® 488 형광 표지로 높은 감도 제공. 단백질 A/G 정제, 4°C 보관, 연구용 전용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:100
Flow Cytometry (Flow)
- Tested Dilution: 5 µL/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KLC264 |
| Immunogen | Recombinant human Ig kappa chain |
| Conjugate | CF® 488 |
| Excitation / Emission Max | 488 / 515 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa).
Kappa and lambda consist of a variable region and a constant region and can be differentiated by the antigenic properties of the constant region.
The ratio of kappa to lambda is approximately 70:30.
Antibodies to the kappa light chain are useful in identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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