Thermo Fisher Scientific ART3 Polyclonal Antibody

Applications

• Western Blot (WB): Assay-dependent
• Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent

Product Specifications

Target Information

Mono-ADP-ribosylation involves the transfer of the ADP-ribose moiety from NAD⁺ to a specific amino acid in the target protein.
The rodent mono-ADP-ribosyltransferase RT6 is a GPI-anchored membrane protein specifically expressed at the cell surface of rat and mouse T lymphocytes.
The predicted 367-amino acid human ART3 protein has an estimated molecular mass of 41.5 kDa and contains:

• A hydrophobic peptide signal at its N terminus
• Three consensus motifs specific to enzymes catalyzing ADP-ribose transfer
• A hydrophobic C-terminal sequence characteristic of a GPI-anchored protein
• A novel motif repeated three times at its C terminus
• One potential glycosylation site

The ART3 and rodent RT6 proteins share 35% amino acid identity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.