Thermo Fisher Scientific ART3 Polyclonal Antibody
ART3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 IHC(P)에서 사용 가능. Rabbit IgG 기반으로 Protein A 정제. -20°C 보관, 연구용 전용 시약.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ART3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Mono-ADP-ribosylation involves the transfer of the ADP-ribose moiety from NAD⁺ to a specific amino acid in the target protein.
The rodent mono-ADP-ribosyltransferase RT6 is a GPI-anchored membrane protein specifically expressed at the cell surface of rat and mouse T lymphocytes.
The predicted 367-amino acid human ART3 protein has an estimated molecular mass of 41.5 kDa and contains:
- A hydrophobic peptide signal at its N terminus
- Three consensus motifs specific to enzymes catalyzing ADP-ribose transfer
- A hydrophobic C-terminal sequence characteristic of a GPI-anchored protein
- A novel motif repeated three times at its C terminus
- One potential glycosylation site
The ART3 and rodent RT6 proteins share 35% amino acid identity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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