Thermo Fisher Scientific CXCL11 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• In sandwich ELISAs, less than 0.2% cross-reactivity with recombinant human CXCL11, recombinant mouse BLC, CRG-2, GCP-2, MIG, PF4, and SDF-1 alpha is observed.
• Reconstitute at 0.2 mg/mL in sterile PBS.
• Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).

Target Information

Interferon-inducible T-cell alpha chemoattractant (I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas, liver, thymus, spleen, lung, small intestine, placenta, and prostate.
Its molecular weight is 8–11 kDa. I-TAC is also known as CXCL11 and IP-9.
This cytokine regulates calcium release and induces chemotactic response in activated T-cells, acting as the dominant ligand for CXC receptor-3.
The gene contains 4 exons and multiple polyadenylation signals, suggesting cell-specific regulation. IFN-gamma is a potent inducer of its transcription, and expression is elevated in patients with AIDS, dementia, and multiple sclerosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.