Thermo Fisher Scientific CXCL11 Polyclonal Antibody
Mouse CXCL11 단백질을 인식하는 Goat Polyclonal Antibody로, Western Blot, ELISA, Neutralization에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 5% trehalose에 보존됩니다. 연구용으로만 사용 가능합니다.
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- PA547767
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1 µg/mL | View 2 publications |
| ELISA (Detection) | 0.1–0.4 µg/mL | - |
| ELISA (Capture) | 0.2–0.8 µg/mL | - |
| Neutralization (Neu) | 2–12 µg/mL | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant mouse CXCL11/I-TAC (Phe22–Met100) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2577164 |
Product Specific Information
- In sandwich ELISAs, less than 0.2% cross-reactivity with recombinant human CXCL11, recombinant mouse BLC, CRG-2, GCP-2, MIG, PF4, and SDF-1 alpha is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).
Target Information
Interferon-inducible T-cell alpha chemoattractant (I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas, liver, thymus, spleen, lung, small intestine, placenta, and prostate.
Its molecular weight is 8–11 kDa. I-TAC is also known as CXCL11 and IP-9.
This cytokine regulates calcium release and induces chemotactic response in activated T-cells, acting as the dominant ligand for CXC receptor-3.
The gene contains 4 exons and multiple polyadenylation signals, suggesting cell-specific regulation. IFN-gamma is a potent inducer of its transcription, and expression is elevated in patients with AIDS, dementia, and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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