Thermo Fisher Scientific Langerin Polyclonal Antibody
Rabbit polyclonal antibody against human Langerin (CD207). Validated for Western blot in human, mouse, and rat samples. Affinity-purified with >95% purity. Supplied as liquid in PBS with 50% glycerol. Suitable for research use only.
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- PA576090
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- pk
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human Langerin (CD207), UniProt ID: Q9UJ71-1, amino acids 1–328 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719817 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. Purity is greater than 95% as determined by SDS-PAGE.
Target Information
Langerin (CD207) is a type II membrane-associated C-type lectin expressed exclusively by Langerhans cells. It recognizes mannose residues via its carbohydrate recognition domain (CRD) and is localized both on the cell surface and intracellularly in association with Birbeck granules. Expression of Langerin induces the formation of membrane structures typical of Birbeck granules, contributing to membrane superimposition and zippering processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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