Thermo Fisher Scientific PSD-95 Monoclonal Antibody (6G6-1C9)
PSD-95 단백질 검출용 Mouse monoclonal antibody (Clone 6G6-1C9). Western blot, ICC/IF, IP 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. 고순도 Protein A 정제, 3.3 mg/mL 농도, -20°C 보관.
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Thermo Fisher Scientific PSD-95 Monoclonal Antibody (6G6-1C9)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | 91 |
| Immunohistochemistry (IHC) | - | 60 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | - | 1 |
| Immunohistochemistry (Frozen) (IHC (F)) | - | 8 |
| Immunocytochemistry (ICC/IF) | 1:500 | 104 |
| Flow Cytometry (Flow) | 2 µg/test | 1 |
| Immunoprecipitation (IP) | Assay-dependent | 9 |
| ChIP assay (ChIP) | - | 1 |
| Neutralization (Neu) | - | 1 |
| Immunomicroscopy (IM) | - | 1 |
| GST Pull Down (GPD) | - | 1 |
| Miscellaneous PubMed (Misc) | - | 2 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | C. elegans, Human, Mouse, Nematode, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6G6-1C9 |
| Immunogen | Purified recombinant rat PSD-95 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.3 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_325399 |
Product Specific Information
MA1-045 has been successfully used in immunofluorescence analysis of PSD95 in human motor neurons derived from iPSCs.
Target Information
Post Synaptic Density 95 kDa (PSD-95), also known as synapse associated protein 90 kDa (SAP90), is a membrane-associated protein found in postsynaptic density of forebrain neurons and certain presynaptic structures in the cerebellum.
It contains three PDZ domains, followed by an SH3 domain and a guanylate kinase homology (GuK) domain.
PSD-95 participates in clustering of NMDA receptors and Shaker-type potassium channels at the synaptic membrane in CNS neurons.
Interaction occurs via C-terminal T/SXV motifs or PDZ-PDZ domain binding, enabling association with NMDA receptors, potassium channels, serotonin receptors, and neuronal nitric oxide synthase (nNOS).
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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