Thermo Fisher Scientific Oxytocin R Polyclonal Antibody
Thermo Fisher Scientific의 Oxytocin R Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 Oxytocin 수용체를 검출할 수 있는 Rabbit IgG 폴리클로날 항체입니다. Western blot, IHC, ELISA에 적합하며 고순도 Protein A 정제 및 안정한 액상 형태로 제공됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse oxytocin receptor, amino acids 325–388 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The oxytocin receptor (OXTR) belongs to the G-protein coupled receptor family. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The receptor consists of 389 amino acids and has a molecular weight of approximately 43 kDa. The oxytocin-oxytocin receptor system plays an important role in uterine contractions during parturition and milk ejection. Oxytocin receptors are expressed in myoepithelial cells of the mammary gland, and in both the myometrium and endometrium of the uterus at the end of pregnancy. Additionally, oxytocin receptors are present in the central nervous system, mediating behaviors such as maternal bonding, social recognition, sexual and aggressive behaviors, and stress response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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